My first friend I came out to when I was 18 ended up giving me up as a friend. She was a Catholic that picked and chose what she found moral, and me being gay didn't sit well with her. What's ironic is that she only did anal because she wanted to stay a "virgin" until marriage and when told me about all the guys that fucked her in the ass didn't judge and cheered her on.
Aside from her though, -every- person I've told over the 7 years since has been really accepting and I've made TONS of friends that replaced her.