On Safety: Poppers are extremely popular in the gay community and in clubs yet only a handful of deaths have ever been reported and those are easily avoided cases of either ingesting the liquid instead of sniffing it or mixing with viagra. Don't do viagra and don't drink the stuff and there's no health risks to speak of. By way of comparison it's way way safer than alcohol.
On How it Feels: Poppers are a vascular dilator which means it opens up blood flow throughout your body. At first you feel your heart start to thump harder and faster as blood flow increases. Then blood rushes to your brain and the extra hit of oxygen gives you a head-rush for 30-60 seconds that makes you feel high, it's a really good but brief feeling you quickly come down from. Then you feel what they call "increased libido" which is kind of a mixture of horny and passive. You want to suck cock or get fucked you're horny but not to cum yourself but to get used. Although you don't really feel anything, it also makes you loosen up so it's easier to take your man anally. So the combination of that "increase libido" feeling and your sphincter relaxing makes it an ideal drug for bottoms - why it's so popular with the gay community. After like 5 minutes or so all feeling is gone and usually you take another hit. The blood rush can cause you to lose your erection, though, making it not great for a top but for some it makes for a more intense orgasm.
