your colon is the last stopm for nutrients and water to remain in the body before the rest is expelled be very careful about putting any kind of beer or mixed drink up your ass and NEVER put hard liquor straight up a persons anus only use saline wash or normal water the4 stuff your colon absorbs doe not go through your liver it goes straight into your blood stream which is why its a far more effective manner to get drunk how ever with out your liver protecting your body and filtering out the toxins eg. alcohol you can get very severe alcohol poisoning very fast with little control as unlike normal drinking you have to drink a lot also if you plan on getting C.Difficile use anti bacterials on your ass cause the flora in there is supposed to be there and helps guard against unwanted lower intestinal problems… and my final point you ingest fecal matter if your giving some one head unless they just washed your going to ingest it your body can deal with it don't worry small amounts are highly unlikely to affect you and anti microbial soaps are bad news they dont kill everything and the small portion that survives is how we get super bugs