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    Is anyone on PrEP? Any side effects?

    HIV & AIDS
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    • H
      harryme last edited by

      Is anyone taking PrEP? Are there known side effects?

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        firkraag last edited by

        I’m on it for almost two years now. I have no side effects. Kidneys function normally, no weight change or anything that I could relate to taking it.

        Cheers!

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          monty last edited by

          I have been on PrEP for the last 14 months now.  I had mild gastric issues for the first 6-8 weeks, but I have no issues now.

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            jbo1 last edited by

            I've been on PrEP for two years. I also had mild gastric issues for 4-6 weeks but nothing else after that.

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              eladuk last edited by

              Ive just started taking prep, im on day 10 now. I am expereincing a mild sore throat, some dizziness and fatigue, which are listed as possible side effects (or im coming with the a cold), other than that I am fine. Ive no energy for sex though and I dont feel like it either :blink: I did have a kidney function test before I started taking it which was fine and I'm due back in March for a recheck to make sure its still ok.

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                BananaWax last edited by

                I was on Truvada for months and experienced horrible nausea the entire time. Switched to Descovy (the newest PrEP med), and I've been completely fine.

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                  boyishguy last edited by

                  This is the second time I've been on truvada, last time was so i was safe during a holiday, this time its ongoing now for 6 weeks, no side effects on both occasions.

                  Most common things to look out for are kidney and liver problems, so get your blood work done before and after you start taking it to monitor its effects. Also any short term side effects usually subside after a week or two, but if they don't then you should stop taking it and consult your doctor.

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                    eladuk last edited by

                    @eladuk:

                    Ive just started taking prep, im on day 10 now. I am expereincing a mild sore throat, some dizziness and fatigue, which are listed as possible side effects (or im coming with the a cold), other than that I am fine. Ive no energy for sex though and I dont feel like it either :blink: I did have a kidney function test before I started taking it which was fine and I'm due back in March for a recheck to make sure its still ok.

                    Just to update that the symptoms I was experiencing had all vanished by the start of the 4th week so for anyone else reading this, that is how it went for me.

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                      zeuri92 @monty last edited by

                      @monty how was your gastric effect? I changed my prep brand and I have Diarrhea for 3 weeks now.

                      bi4smooth 1 Reply Last reply Reply Quote 0
                      • bi4smooth
                        bi4smooth @zeuri92 last edited by

                        @zeuri92 said in Is anyone on PrEP? Any side effects?:

                        @monty how was your gastric effect? I changed my prep brand and I have Diarrhea for 3 weeks now.

                        I've been on the original Truvada PrEP since 2015... no side effects, ever.
                        I've been offered some of the newer ones - I've asked my Dr.: Are the newer ones better? (no), safer? (unknown), cheaper? (not for me - my insurance pays 100% of it either way). So, if there's no REAL benefit, why would I risk changing?

                        That's my experience - with my Dr. Your mileage may vary.

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                          Zeitgeist last edited by

                          No side-effects, but I do think that you should get regular tests (every 3 months) for liver & kidney function in order to minimise any possible damage.

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                            di3di3di3 last edited by

                            no i dont use prep and use condoms for everything sex, including oral sex

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                              umhl last edited by

                              The most common Side Effect is is nausea and diarrhea. Most symptoms resolve within one to two months. To avoid symptoms, take before bed (if you are asleep... how do you know you had nausea?) or on a full stomach like the cherry on top of the ice cream at the end of a large meal.

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                              • PopperPossum
                                PopperPossum last edited by

                                On a Truvada generic for 4 months now, had some nausea the first week I took it but nothing after that. Got all my guts checked out at 3 months and everything was normal.

                                "Money doesn't make you happy but it lets you be unhappy for a bit longer."
                                -Disco Elysium

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                                • Mrker1234
                                  Mrker1234 last edited by

                                  I am not having sex that often, so have been on PrEP 2-1-1 and only take truvada as required. It minimizes how much I use which greatly minimizes any possible side effects.

                                  The type of “on-demand” PrEP that has been studied is the “2-1-1” schedule. This means taking 2 pills 2-24 hours before sex, 1 pill 24 hours after the first dose, and 1 pill 24 hours after the second dose.

                                  https://www.cdc.gov/hiv/basics/prep/on-demand-prep.html

                                  Oh, if you have a weekend visitor 😃 it is 2 to get to base level and 1 each day having sex and for the next 2 days, not 2 each day you get fucked.

                                  bi4smooth 1 Reply Last reply Reply Quote 0
                                  • bi4smooth
                                    bi4smooth @Mrker1234 last edited by

                                    @mrker1234

                                    While there IS some evidence that the 2-1-1 dosing of PrEP can work, it has not been studied well...

                                    On the cited CDC page, it states clearly: "This type of use is not currently part of CDC’s guidelines for PrEP use, which still recommends using PrEP as prescribed for those at risk for HIV. Taking PrEP as prescribed is currently the only FDA-approved schedule for taking PrEP to prevent HIV. When taken as prescribed, PrEP is highly effective for preventing HIV."

                                    That said, my perspective about PrEP is that it's use allows the individual to TAKE CHARGE of THEIR OWN sexual health! Rather than "trusting" the partner to accurately report their own HIV status and/or maintain constant and proper condom use, the person who chooses PrEP asserts a level of control previously unavailable.

                                    If YOU are comfortable with the 2-1-1 regimen for PrEP, then that's your decision! Good for you for at least taking control! Unlike COVID-19 masks and vaccines, the only person you're "protecting" with PrEP is yourself!

                                    In reference to the original question: I've been on PrEP since 2015 - over 95% compliant (never missed more than 1 single day, but have from time to time lost a day in the shuffle of day-to-day life!)... and I have had no noticeable side effects.

                                    Mrker1234 1 Reply Last reply Reply Quote 0
                                    • Mrker1234
                                      Mrker1234 @bi4smooth last edited by Mrker1234

                                      @bi4smooth The CDC report, which tries to be the most stringent source, also states "Some health departments in the United States and some health organizations in Europe and Canada are offering guidance for “on-demand” PrEP as an alternative to daily PrEP for gay and bisexual men at risk for HIV."

                                      Sometimes it is simple math. I'm older and have sex very occasionally. I wouldn't go on PrEP if it meant taking 365 pills a year instead of the 40 I use for the 10 weekends I may have sex. That amount of chemicals being ingested unnecessarily seems to be even riskier than depending on just condoms.

                                      Obviously everyone's mileage may vary. I'm looking at almost a 90% reduction of chemicals in my body. Someone having sex every week or several times a month, will have significantly less benefit to going "on demand".

                                      bi4smooth 1 Reply Last reply Reply Quote 0
                                      • bi4smooth
                                        bi4smooth @Mrker1234 last edited by

                                        @mrker1234 said in Is anyone on PrEP? Any side effects?:

                                        @bi4smooth The CDC report, which tries to be the most stringent source, also states "Some health departments in the United States and some health organizations in Europe and Canada are offering guidance for “on-demand” PrEP as an alternative to daily PrEP for gay and bisexual men at risk for HIV."

                                        Sometimes it is simple math. I'm older and have sex very occasionally. I wouldn't go on PrEP if it meant taking 365 pills a year instead of the 40 I use for the 10 weekends I may have sex. That amount of chemicals being ingested unnecessarily seems to be even riskier than depending on just condoms.

                                        Obviously everyone's mileage may vary. I'm looking at almost a 90% reduction of chemicals in my body. Someone having sex every week or several times a month, will have significantly less benefit to going "on demand".

                                        Please don't take my comments wrongly: PrEP - no matter how you take it - is doing something to protect one's self, and I APPLAUD that! It's wonderful that we have options, and the science is continuing!

                                        I agree that the CDC often takes an overly cautious tone - but it's the opinions of the FDA that matter here: they control the ability of physicians to prescribe the medications. (Two very separate federal agencies, with different goals, methods, and agendas!)

                                        I choose to continue to take my PrEP daily - even though I've been in a monogamous relationship for a little over 2-years now. It's not that I don't trust my partner, it's that I'm unwilling to risk HIV - either with him or anyone else - period! I'm 58... and I presume I'll take daily PrEP until my dick falls off and my ass closes up! 🙂 (Always the optimist!)

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                                          Bodybuilder7 last edited by

                                          I'm not on Prep but I always use condoms when I have sex & if it's oral, I stay with 1 person I could trust.

                                          My good friend is on PrEP & he did mention gastric mild concerns, as one member here discussed.

                                          Hope this helps!

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                                            stam8 @BananaWax last edited by

                                            @BananaWax Hi, so you mean your truvada side effects never went away for those 4 months of taking it? Also, do you need to get kidney function checked regularly with descovy?

                                            thank you so much

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