Stay away from Gay & Muslim.
Other topics in Religion don't seem to be toxic.
Granted, I do not wish to debate religion. I do interfaith work and enjoy conversations but the idea that the only way that you will speak with someone whose experience is different than yours is by trying to force them into your opinion is not pleasant.
One of the phrases I like from (English translations/interpretations of) the Quran is "Allah has made you separate peoples and nations so that you can learn from one another; not that you should despise one another." I like hearing what the process of Lent means to a Christian and sharing what the process of the 49 days between Pesach (Leaving Egypt) and Shevuoth (Recieving the Torah) means to me. If you're interested in civil conversation, let's talk.